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When facial fat disappears, many people assume they need bigger lips, more filler, or veneers that are whiter and larger

The incidence of serious adverse events (e.g., cardiovascular events, severe gastrointestinal reactions, infections, etc.) was higher for PEX168 (OR=0.54), tirzepatide 15mg (OR=0.15), and oral semaglutide 14mg (OR=0.09) than for other GLP-1RAs, and tirzepatide 15mg and oral semaglutide 14mg will have serious adverse events but at a lower risk

Constipation affected 22% to 25%

An important clinical paradox: elevated serum B12 can sometimes coexist with functional B12 deficiency

The glucagon receptor component of mazdutide is likely responsible for much of the liver benefit